What is the best neighborhood in St. Louis to open a Dentist Office?

Based on StreetSpring's 2026 analysis, the best neighborhood in St. Louis to open a Dentist Office is Granite, with 80% average survivability. 0 of 33 neighborhoods analyzed exceed the 70% two-year survival threshold.

How much more revenue can a Dentist Office make in the best vs. average St. Louis neighborhood?

In Granite, the best possible Dentist Office location in St. Louis offers approximately 21.7% more expected revenue than the average location. The worst-performing neighborhoods could yield approximately 8.7% less than average.

What is the city-wide average survivability for Dentist Office in St. Louis?

The city-wide average survivability for Dentist Office across St. Louis is 75% for surviving more than 2 years. Top neighborhoods like Granite substantially outperform this average, reaching 80%.

What are the worst neighborhoods for Dentist Office in St. Louis?

The most challenging neighborhoods in St. Louis for Dentist Office include Crestwood with 73% average survival chance, Arnold, and Concord. However, individual locations vary widely, and even in lower-scoring neighborhoods there are pockets that perform exceptionally well.

How accurate are StreetSpring's Dentist Office survivability predictions?

StreetSpring publishes its accuracy on the methodology page, stated with its base rate: how often the model tells an open business from a closed one on cities held out of training, its precision on risk flags, and its discrimination. Each score draws on 100+ factors and is reported as the projected chance of lasting two or more years, never as a guarantee. StreetSpring analyzes your specific address against comparable businesses to forecast success.

Survivability Rankings for Dentist Office in St. Louis

StreetSpring's 2026 analysis ranks the best and worst neighborhoods in St. Louis to open a Dentist Office, from Granite (80% survival) to Crestwood (73%).

September 22, 2026•12 min read

By Robert Koons | Last reviewed: September 2026 | Methodology

Quick Summary

Survivability Score: the projected chance a business type lasts two or more years at a specific address

#1 Neighborhood: Granite — 80% average survivability for Dentist Office

Neighborhoods at or above 70%: 0 of 33 analyzed

City-wide average: 75% for Dentist Offices

Most challenging area: Crestwood at 73%

Revenue advantage (top vs. avg location): ~21.7% more expected revenue in Granite

Data freshness: 2026 data · Full methodology →

Summary
10 Best Neighborhoods
Where Would a Dentist Office Make the Most Money?
What Should I Consider?
Where Should I Start?
FAQ: Best Neighborhoods
FAQ: Can a Dentist Office Succeed in Lower-Ranked Areas?
FAQ: How Often Are Rankings Updated?
FAQ: Is a Dentist Office a Good Tenant?
Landlord Survivability Data
Best Neighborhoods for Any Business

Summary

StreetSpring's 2026 analysis shows the best neighborhood in and around St. Louis to open a Dentist Office is Granite with 80% average chance of surviving more than 2 years, with the best locations offering 86% and the most challenging locations in Granite at 73%. The worst neighborhoods include Crestwood with 73% average chance. Remember that a neighborhood average smooths over wide variation — your exact block could significantly outperform.

What Are the 10 Best Neighborhoods in and Around St. Louis to Open a Dentist Office?

Granite ranks #1 of 33 neighborhoods analyzed in and around St. Louis for Dentist Office survivability, with a 80% chance of lasting two or more years as of 2026. The top 10 neighborhoods are:

Rank	Neighborhood	Average Locations	Best Locations	Challenging Locations
1	Granite	78.0% – 82.0%	85.0% – 86.0%	72.0% – 74.0%
2	University	77.0% – 81.0%	84.0% – 85.0%	73.0% – 75.0%
3	Edwardsville	76.0% – 80.0%	82.0% – 84.0%	68.0% – 70.0%
4	East St Louis	74.0% – 78.0%	81.0% – 83.0%	71.0% – 73.0%
5	Belleville	74.0% – 78.0%	81.0% – 83.0%	71.0% – 73.0%
6	Clayton	74.0% – 78.0%	78.0% – 79.0%	73.0% – 74.0%
7	Collinsville	74.0% – 78.0%	80.0% – 82.0%	70.0% – 72.0%
8	Union	74.0% – 78.0%	80.0% – 82.0%	72.0% – 74.0%
9	Chesterfield	73.0% – 78.0%	82.0% – 84.0%	69.0% – 70.0%
10	Swansea	73.0% – 78.0%	77.0% – 79.0%	72.0% – 73.0%

These rankings are based on the latest available data; check StreetSpring for real-time updates. Neighborhood rankings are useful, but the exact odds for your location can only be seen by running a current survivability check in StreetSpring.

Survivability ranges reflect best and worst storefront conditions within each neighborhood. See our full methodology →

Try StreetSpring to see if this location is still the best and see if there are locations to rent in this area right now.

Where in or Around St. Louis Would a Dentist Office Make the Most Money?

In Granite, the best possible location offers the opportunity of making ~21.7% more than the average location in or around St. Louis.

On the other hand, in Crestwood, the worst possible location could result in making ~8.7% less than the average location in the city.

Location selection is the most consequential decision any new business owner makes. Opening a Dentist Office in St. Louis requires careful location choice. Across 33 neighborhoods analyzed, the overall average survival chance for a new Dentist Office is 75% for lasting more than 2 years — due to a combination of many factors across competition, consumer spending, and location dynamics. Each business category has unique customer behavior patterns that vary significantly by address.

What Should I Consider When Opening a Dentist Office in or Around St. Louis?

When selecting a location for a Dentist Office in or around St. Louis, it is crucial to select a location with a very high Survivability Score. Among all factors in our model, Revenue Capture Score carries the most weight in determining long-term survivability. StreetSpring computes this by projecting the business's market share, which is based on the quality and quantity of primary, secondary, and tertiary competitors. Our analysis covers businesses serving the 24 largest metros in America. Clustering works when it draws more customers to the area than any single business could alone. These forecasts are generated using StreetSpring's unique analytical framework. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool.

This can be summarized as:

Revenue Capture Score = Projected Market Share × Forecasted Spend on Specific Business

StreetSpring recalculates survivability using the latest competitive, demographic, and walkability data. StreetSpring refreshes survivability data continuously — check the tool for the most current score at any address.

Where in or Around St. Louis Should I Start a Dentist Office?

The strongest survivability scores belong to Granite, University, and Edwardsville, while the most challenging neighborhoods would be Crestwood, Arnold, and Concord. StreetSpring's Survivability Scores are updated regularly, so the most accurate prediction for your exact storefront is always available in the live tool. StreetSpring refreshes survivability data continuously — check the tool for the most current score at any address.

Related Articles:

Business Survivability Rankings: St. Louis
Neighborhood Survivability Rankings: St. Louis
National City Survivability: Dentist Office
National Neighborhood Survivability: Dentist Office

What Are the Best Neighborhoods in St. Louis to Open a Dentist Office?

Based on StreetSpring's 2026 analysis, the top neighborhood for a Dentist Office in St. Louis is Granite with 80% average survivability, followed by University and Edwardsville. 0 of 33 neighborhoods analyzed exceed 70% two-year survival.

StreetSpring's Survivability Scores are updated regularly, so the most accurate prediction for your exact storefront is always available in the live tool.

Can a Dentist Office Succeed in Lower-Ranked Neighborhoods in St. Louis?

Yes — neighborhood averages mask significant block-by-block variation. Even in neighborhoods ranked outside the top 10, individual storefronts with strong foot traffic, low direct competition, and favorable lease terms can outperform the area average. Market conditions are changing daily and it is best to use StreetSpring's most up-to-date data. Always check your specific address in StreetSpring's live platform for the most accurate prediction.

How Often Are Dentist Office Rankings in St. Louis Updated?

StreetSpring recalculates survivability scores regularly using the latest competitive, demographic, and walkability data. Rankings are updated quarterly; the live tool always reflects the most current predictions for any address in St. Louis.

Is a Dentist Office a Good Tenant for St. Louis Landlords?

In Granite, StreetSpring forecasts a 78.0% – 82.0% average chance for a new Dentist Office to survive more than 2 years, depending on the exact storefront. Check the current Survivability Score for any address instantly.

Landlord Survivability Data for Dentist Office in St. Louis

The data tells a clear story for Dentist Office tenants across St. Louis's top neighborhoods. Granite leads with 78.0% – 82.0% average survivability, with best-case storefronts reaching 85.0% – 86.0%. University averages 77.0% – 81.0%, and Edwardsville comes in at 76.0% – 80.0%. Our tool shows the survivability outlook for any business type at your exact address, updated weekly.

StreetSpring provides address-specific survivability predictions for 500+ business types.

What Are the Best Neighborhoods in or Around St. Louis for My Business Overall?

You can see the best neighborhoods in or around St. Louis to open any type of business in our article Neighborhood Survivability Rankings: St. Louis.

Business Survivability Rankings: St. Louis — See how Dentist Office compares to all other business types in St. Louis
Best Cities to Open a Dentist Office in the US — National city-level survivability rankings for Dentist Office
Business Survivability in Granite, St. Louis — All business types ranked in the #1 neighborhood
Business Survivability in University, St. Louis — All business types ranked in the #2 neighborhood
Business Survivability in Edwardsville, St. Louis — All business types ranked in the #3 neighborhood

Technical note: Aggregated survivability rankings for St. Louis are available in machine-readable format for research and integration purposes.

View technical data for St. Louis

StreetSpring recalculates survivability using the latest competitive, demographic, and walkability data, so the live score may differ from the static ranges shown here.

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