Business Survivability in East St Louis, St. Louis
StreetSpring's 2026 analysis finds that the best business to open in East St Louis is a Veterinary Clinic with a ~81% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Veterinary Clinic in East St Louis (~81% average survival rate, ~89% at best locations)
- Neighborhood rank: #19 across all neighborhoods in and around St. Louis
- Neighborhood average: ~78% two-year survival across all business types
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: September 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is East St Louis a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in East St Louis is a Veterinary Clinic with a ~81% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a ~89% chance; next is a Steakhouse with a 79.11% chance, followed by a Deli with a 78.75% chance.
Is East St Louis a good place to start a business?
Out of all neighborhoods analyzed in and around St. Louis, East St Louis ranks #19 for business survivability with a ~78% average Survivability Score.
- The top business types in East St Louis, when placed at their ideal addresses, achieve survivability rates ~28% above the neighborhood-wide average.
- But at poorly chosen addresses within East St Louis, even the top-ranked business types can fall well below the neighborhood average. Location selection remains critical — a promising concept at the wrong spot still carries significant risk.
Employment and vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in East St Louis?
Using StreetSpring, you can identify the exact address in East St Louis that gives your specific business concept the highest survivability score. According to StreetSpring's 2026 data, this is the optimal address for a Veterinary Clinic in East St Louis:
The highlighted area represents the address in East St Louis that StreetSpring's 2026 analysis ranks highest for a Veterinary Clinic survivability. Even the best-ranked neighborhoods contain locations that underperform — and the worst-ranked ones have hidden gems. StreetSpring's scoring incorporates hundreds of inputs, including competitive quality and density, projected consumer spending, Revenue Capture Score, and local demand patterns.
Check if this location is still available →
What are the best businesses to open in East St Louis?
| # | Business type | Chance of lasting two or more years |
|---|---|---|
| 1 | Veterinary Clinic | 80.65% |
| 2 | Steakhouse | 79.11% |
| 3 | Deli | 78.75% |
| 4 | Hawaiian Restaurant | 78.72% |
| 5 | Dance Club | 75.76% |
| 6 | Smoke Shop | 74.76% |
| 7 | Pet Boarding Facility | 74.67% |
| 8 | Pet Grooming Shop | 74.05% |
| 9 | Laundromat | 72.99% |
| 10 | Watch Store or Repair Shop | 72.85% |
#1-5: Highest Survivability in East St Louis
- Veterinary Clinic is ranked #1 for top businesses to open in East St Louis: 80.65% chance on average, best at ~89%, challenging at ~67%.
- Steakhouse — ~72%–~84% survivability range, with an average of 79.11% across East St Louis.
- Opening a Deli in East St Louis shows 78.75% average survivability. Top locations reach ~84%; lower-end sites show ~71%.
- Hawaiian Restaurant (Ranked #4): 78.72% average in East St Louis. Best-case storefronts: ~84%. Challenging locations: ~71%.
- Dance Club is ranked #5 for top businesses to open in East St Louis: 75.76% chance on average, best at ~85%, challenging at ~61%.
#6-10: Strong Performers in East St Louis
- Smoke Shop — ~61%–~84% survivability range, with an average of 74.76% across East St Louis.
- Opening a Pet Boarding Facility in East St Louis shows 74.67% average survivability. Top locations reach ~84%; lower-end sites show ~60%.
- Pet Grooming Shop (Ranked #8): 74.05% average in East St Louis. Best-case storefronts: ~83%. Challenging locations: ~59%.
- Laundromat is ranked #9 for top businesses to open in East St Louis: 72.99% chance on average, best at ~80%, challenging at ~61%.
- Watch Store or Repair Shop — ~62%–~81% survivability range, with an average of 72.85% across East St Louis.
Top 3 Compared Nationally
- Veterinary Clinic — See how this compares to other cities →
- Steakhouse — See how this compares to other cities →
- Deli — See how this compares to other cities →
How much money could a business in East St Louis make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, picking the highest-scoring storefront in the neighborhood in East St Louis could lead to you making ~28% more than if you selected an average location, and ~1% more than if you selected one of the worst locations.
How StreetSpring calculates location value
- The right address for one business type may be the wrong one for another — always evaluate fit for your specific concept.
- Among all variables that affect business outcomes, location has the highest predictive weight in our models.
- Across every business type we've analyzed, location quality as measured by Survivability Score is the strongest predictor of financial performance.
- StreetSpring generates location-specific predictions tailored to your exact site.
What businesses should open next in East St Louis?
The top businesses to open next in East St Louis:
- Veterinary Clinics — 80.65% average survival rate, ~89% at the best address
- Steakhouses — 79.11% average survival rate
- Delis — 78.75% average survival rate
Even the best-ranked neighborhoods contain locations that underperform — and the worst-ranked ones have hidden gems. The model draws from 100+ location-specific factors to generate each survivability score. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. Survivability scores are live, not static — StreetSpring updates them weekly. Visit the tool to see what's currently available in East St Louis and how each address is scoring right now.
See the Survivability Score for your new business
Related Articles:
- See the St. Louis Business Survivability Rankings
- See the St. Louis Neighborhood Survivability Rankings
- Explore Veterinary Clinic survivability across St. Louis neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in East St Louis.
What type of business should you rent your East St Louis storefront to?
Based on 2026 survivability scores across all business types in East St Louis, the top three tenant categories for landlords are Veterinary Clinics, Steakhouses, and Delis.
- Among all variables that affect business outcomes, location has the highest predictive weight in our models.
- StreetSpring generates location-specific predictions tailored to your exact site. With StreetSpring, you can rank every potential tenant type by survivability score at your property address before committing to a lease.
Related: See How Landlord Representatives in St. Louis Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your East St Louis storefront to a Veterinary Clinic?
The data shows a Veterinary Clinic is the safest long-term bet for a East St Louis storefront. Top locations reach ~89% survivability; the least favorable addresses in this neighborhood score around ~67%.
- StreetSpring generates location-specific predictions tailored to your exact site.
What should I consider when opening a business in East St Louis?
In East St Louis, the single most important factor in your site-selection decision is the Survivability Score of the specific address you're evaluating.
- Revenue Capture Score is what separates locations that look similar on the surface but produce dramatically different business outcomes.
- The underlying models are StreetSpring's own — built, trained, and maintained using data external platforms cannot access.
- StreetSpring's address-level survivability data is available free of charge — start with your top candidate locations in East St Louis.
See the best place for your business at StreetSpring.
StreetSpring combines proprietary data with advanced analytics to predict which businesses will succeed. Aggregated survivability rankings for St. Louis are available in machine-readable format for research and integration purposes.
Full dataset for St. Louis: /resources/data/st-louis-survivability-scores-2026.csv — includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.