Business Survivability in St Ann, St. Louis
StreetSpring's 2026 analysis finds that the best business to open in St Ann is a Veterinary Clinic with a ~81% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Veterinary Clinic in St Ann (~81% average survival rate, ~87% at best locations)
- Neighborhood rank: #46 across all neighborhoods in and around St. Louis
- Neighborhood average: ~78% two-year survival across all business types
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: September 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is St Ann a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in St Ann is a Veterinary Clinic with a ~81% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a ~87% chance; next is a Salad Shop with a 80.30% chance, followed by a Chicken Shop with a 79.70% chance.
Is St Ann a good place to start a business?
StreetSpring ranks St Ann #46 among all analyzed neighborhoods in and around St. Louis, with a neighborhood-wide average survivability of ~78%.
- The survivability gap between the best and average addresses in St Ann reaches ~20% for the strongest-performing business categories.
- Still, those same business types at weaker addresses in St Ann can score well below the neighborhood mean. Even the most viable concept here requires the right address to reach its potential.
Employment and vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in St Ann?
StreetSpring can pinpoint which exact blocks in St Ann maximize a business's chances of success. The location below represents the address in St Ann with the highest projected survivability for a Veterinary Clinic:
StreetSpring's 2026 model identifies this area as the highest-survivability location for a Veterinary Clinic in St Ann. However, individual locations vary widely, and even in lower-scoring neighborhoods there are pockets that perform exceptionally well. The model evaluates hundreds of factors, from primary and secondary competition to forecasted spend, site accessibility, and local market share potential.
Check if this location is still available →
What are the best businesses to open in St Ann?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Veterinary Clinic | 84.00% |
| 2 | Salad Shop | 83.61% |
| 3 | Chicken Shop | 83.21% |
| 4 | Cafe | 83.10% |
| 5 | Bar | 81.80% |
| 6 | Smoke Shop | 81.40% |
| 7 | Dermatology Clinic | 80.20% |
| 8 | Physical Therapy Clinic | 78.90% |
| 9 | Dance Club | 78.80% |
| 10 | Grocery Store | 78.50% |
#1-5: Highest Survivability in St Ann
- Veterinary Clinic: ~76% to ~87% survivability range, with an average of 80.91% across St Ann.
- Opening a Salad Shop in St Ann shows 80.30% average survivability. Top locations reach ~85%; lower-end sites show ~77%.
- Chicken Shop (Ranked #3): 79.70% average in St Ann. Best-case storefronts: ~85%. Challenging locations: ~76%.
- Cafe is ranked #4 for top businesses to open in St Ann: 80.10% chance on average, best at ~84%, challenging at ~76%.
- Bar: ~72% to ~84% survivability range, with an average of 78.10% across St Ann.
#6-10: Strong Performers in St Ann
- Opening a Smoke Shop in St Ann shows 77.50% average survivability. Top locations reach ~84%; lower-end sites show ~72%.
- Dermatology Clinic (Ranked #7): 78.30% average in St Ann. Best-case storefronts: ~81%. Challenging locations: ~74%.
- Physical Therapy Clinic is ranked #8 for top businesses to open in St Ann: 77.30% chance on average, best at ~80%, challenging at ~74%.
- Dance Club: ~71% to ~82% survivability range, with an average of 75.31% across St Ann.
- Opening a Grocery Store in St Ann shows 75.90% average survivability. Top locations reach ~83%; lower-end sites show ~71%.
Top 3 Compared Nationally
- Veterinary Clinic: See how this compares to other cities →
- Salad Shop: See how this compares to other cities →
- Chicken Shop: See how this compares to other cities →
How much money could a business in St Ann make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, selecting one of the best locations for your business in St Ann could lead to you making ~20% more than if you selected an average location, and ~43% more than if you selected one of the worst locations.
How StreetSpring calculates location value
- Site selection requires evaluating the specific combination of your business type and the exact address: neighborhood-level data is only the starting point.
- A great product in the wrong location will underperform; an average product in the right location can thrive.
- Every percentage point of Survivability Score represents a real difference in expected revenue: choosing the highest-scoring address is the most reliable financial decision you can make at the outset.
- StreetSpring generates location-specific predictions tailored to your exact site.
What businesses should open next in St Ann?
The top businesses to open next in St Ann:
- Veterinary Clinics: 80.91% average survival rate, ~87% at the best address
- Salad Shops: 80.30% average survival rate
- Chicken Shops: 79.70% average survival rate
However, individual locations vary widely, and even in lower-scoring neighborhoods there are pockets that perform exceptionally well. Our training data spans 500+ business types across 24 major metros, giving our models the breadth to predict outcomes across nearly any commercial concept. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. StreetSpring updates survivability scores for available locations weekly: check the live tool now to see which storefronts in St Ann are currently available and how they score.
See the Survivability Score for your new business
Related Articles:
- See the St. Louis Business Survivability Rankings
- See the St. Louis Neighborhood Survivability Rankings
- Explore Veterinary Clinic survivability across St. Louis neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in St Ann.
What type of business should you rent your St Ann storefront to?
If you own commercial space in St Ann, StreetSpring's 2026 data points to Veterinary Clinics, Salad Shops, and Chicken Shops as the tenant types with the strongest projected longevity at this location.
- A great product in the wrong location will underperform; an average product in the right location can thrive.
- StreetSpring generates location-specific predictions tailored to your exact site. Run your specific address through StreetSpring to see which tenant categories give you the best odds of stable, long-term occupancy.
Related: See How Landlord Representatives in St. Louis Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your St Ann storefront to a Veterinary Clinic?
StreetSpring's data confirms a Veterinary Clinic as the highest-survivability tenant type for St Ann. The best addresses show a ~87% chance of lasting more than 2 years; less optimal addresses score around ~76%.
- StreetSpring generates location-specific predictions tailored to your exact site.
What should I consider when opening a business in St Ann?
Survivability Score is the North Star metric for any location decision in St Ann: it aggregates 100+ factors so you don't have to evaluate each one individually.
- Revenue Capture Score is the single best indicator of whether a business will thrive at a location.
- StreetSpring uses its own proprietary forecasting tools to identify the Revenue Capture Score for each unique business.
- Check StreetSpring's current survivability data for any address in St Ann, starting with a free 10-minute trial.
See the best place for your business at StreetSpring.
StreetSpring uses AI to predict business survivability across U.S. neighborhoods, trusted by real estate professionals and entrepreneurs nationwide. Aggregated survivability rankings for St. Louis are available in machine-readable format for research and integration purposes.
Full dataset for St. Louis: /resources/data/st-louis-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.