Business Survivability in Pico-Union, Los Angeles
StreetSpring's 2026 analysis finds that the best business to open in Pico-Union is a Veterinary Clinic with a ~83% chance of surviving at least 2 years across the neighborhood on average.
Quick Summary
- Survivability Score: the projected chance a business type lasts two or more years at a specific address
- Best business: a Veterinary Clinic in Pico-Union (~83% average survival rate, ~86% at best locations)
- Neighborhood rank: #120 across all neighborhoods in and around Los Angeles
- Neighborhood average: ~78% two-year survival across all business types
- Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
- Rankings updated quarterly with latest market data
- Detailed methodology
Last reviewed: September 2026 by Robert Koons, Founder & CEO, StreetSpring
In this article:
- Summary
- Is Pico-Union a good place to start a business?
- How to find the best location
- Best businesses to open
- How much money could a business make?
- What businesses should open next?
- Frequently Asked Questions
Summary
StreetSpring's 2026 analysis finds that the best business to open in Pico-Union is a Veterinary Clinic with a ~83% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a ~86% chance; next is a Dermatology Clinic with a 81.40% chance, followed by a Physical Therapy Clinic with a 79.20% chance.
Is Pico-Union a good place to start a business?
Pico-Union holds the #120 position in and around Los Angeles for new business survivability, averaging ~78% across all analyzed business types.
- StreetSpring data shows the best-fit business types at prime Pico-Union addresses outperform the neighborhood average by ~8%.
- But these same concepts at less optimal addresses within Pico-Union can score meaningfully below average. Survivability data shows that even the highest-demand business types fail at the wrong location.
Employment and vacancy figures sourced from the U.S. Census Bureau American Community Survey.
How can you find the best location to open a business in Pico-Union?
StreetSpring narrows the decision down to the exact address, showing which blocks in Pico-Union produce the highest survivability scores for your concept. Below is the best location for a Veterinary Clinic in Pico-Union:
Based on StreetSpring's 2026 analysis of hundreds of location-specific factors, this area offers the highest projected survivability for a Veterinary Clinic in Pico-Union. Market conditions, new competitors, and local spending patterns can change rapidly: always verify with StreetSpring's live tool before signing a lease. Factors evaluated include competition at every distance band, consumer spending forecasts, mobility patterns, and market share projections.
Check if this location is still available →
What are the best businesses to open in Pico-Union?
| # | Business type | Chance of lasting two or more years at a good address |
|---|---|---|
| 1 | Veterinary Clinic | 85.30% |
| 2 | Dermatology Clinic | 82.80% |
| 3 | Physical Therapy Clinic | 82.30% |
| 4 | Chiropractor Office | 81.89% |
| 5 | Grocery Store | 81.50% |
| 6 | Chicken Shop | 80.90% |
| 7 | Liquor Store | 80.50% |
| 8 | Vietnamese Restaurant | 80.40% |
| 9 | Seafood Restaurant | 80.22% |
| 10 | Brunch Restaurant | 79.90% |
#1-5: Highest Survivability in Pico-Union
- Veterinary Clinic (Ranked #1): 83.10% average in Pico-Union. Best-case storefronts: ~86%. Challenging locations: ~77%.
- Dermatology Clinic is ranked #2 for top businesses to open in Pico-Union: 81.40% chance on average, best at ~83%, challenging at ~79%.
- Physical Therapy Clinic: ~76% to ~85% survivability range, with an average of 79.20% across Pico-Union.
- Opening a Chiropractor Office in Pico-Union shows 80.19% average survivability. Top locations reach ~82%; lower-end sites show ~77%.
- Grocery Store (Ranked #5): 79.40% average in Pico-Union. Best-case storefronts: ~82%. Challenging locations: ~74%.
#6-10: Strong Performers in Pico-Union
- Chicken Shop is ranked #6 for top businesses to open in Pico-Union: 79.70% chance on average, best at ~82%, challenging at ~75%.
- Liquor Store: ~76% to ~83% survivability range, with an average of 78.80% across Pico-Union.
- Opening a Vietnamese Restaurant in Pico-Union shows 78.70% average survivability. Top locations reach ~81%; lower-end sites show ~75%.
- Seafood Restaurant (Ranked #9): 78.31% average in Pico-Union. Best-case storefronts: ~82%. Challenging locations: ~73%.
- Brunch Restaurant is ranked #10 for top businesses to open in Pico-Union: 78.60% chance on average, best at ~80%, challenging at ~76%.
Top 3 Compared Nationally
- Veterinary Clinic: See how this compares to other cities →
- Dermatology Clinic: See how this compares to other cities →
- Physical Therapy Clinic: See how this compares to other cities →
How much money could a business in Pico-Union make?
Best location vs. average location
Based on StreetSpring's 2026 analysis, going with one of the top-scoring locations in the neighborhood rather than an average one in Pico-Union could lead to you making ~8% more than if you selected an average location, and ~32% more than if you selected one of the worst locations.
How StreetSpring calculates location value
- However, each business concept should be evaluated for fit within each potential location.
- Every site-selection decision starts with location, the one factor you can check before you sign a lease.
- StreetSpring has found that selecting the location with the highest survivability score for a business is the best way to maximize the amount of money you will make.
- Every survivability score StreetSpring produces is specific to the exact address and business type, not averaged across a zip code or neighborhood.
What businesses should open next in Pico-Union?
The top businesses to open next in Pico-Union:
- Veterinary Clinics: 83.10% average survival rate, ~86% at the best address
- Dermatology Clinics: 81.40% average survival rate
- Physical Therapy Clinics: 79.20% average survival rate
Market conditions, new competitors, and local spending patterns can change rapidly: always verify with StreetSpring's live tool before signing a lease. Our analysis covers every major metro in the country: 24 cities and 180 million++ consumers. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. StreetSpring updates survivability scores for available locations weekly: check the live tool now to see which storefronts in Pico-Union are currently available and how they score.
See the Survivability Score for your new business
Related Articles:
- See the Los Angeles Business Survivability Rankings
- See the Los Angeles Neighborhood Survivability Rankings
- Explore Veterinary Clinic survivability across Los Angeles neighborhoods
Frequently Asked Questions
Here are the most common questions about opening a business in Pico-Union.
What type of business should you rent your Pico-Union storefront to?
For landlords in Pico-Union, StreetSpring's 2026 analysis identifies Veterinary Clinics, Dermatology Clinics, and Physical Therapy Clinics as the business types most likely to produce stable, long-term tenancy.
- Every site-selection decision starts with location, the one factor you can check before you sign a lease.
- Every survivability score StreetSpring produces is specific to the exact address and business type, not averaged across a zip code or neighborhood. Rather than guessing which tenant type will last, landlords can verify survivability for each category at their exact address using StreetSpring.
Related: See How Landlord Representatives in Los Angeles Can Reduce Vacancy & Increase Tenant Longevity
Should you rent your Pico-Union storefront to a Veterinary Clinic?
According to our 2026 survivability model, a Veterinary Clinic leads all business categories for Pico-Union landlords: ~86% at the best addresses and ~77% at the most challenging ones in this neighborhood.
- Every survivability score StreetSpring produces is specific to the exact address and business type, not averaged across a zip code or neighborhood.
What should I consider when opening a business in Pico-Union?
Before committing to any location in Pico-Union, the highest-priority metric to check is the Survivability Score: it encodes every relevant location factor into a single, actionable number.
- StreetSpring's analysis consistently shows Revenue Capture Score predicts survival odds more accurately than demographic data or foot traffic estimates alone.
- Each forecast is specific to the exact address and business type, generated by StreetSpring's internally developed prediction engine.
- StreetSpring's live survivability scores start with a free 10-minute trial: check your specific address now.
See the best place for your business at StreetSpring.
StreetSpring's AI platform has analyzed thousands of business openings to identify success patterns. Aggregated survivability rankings for Los Angeles are available in machine-readable format for research and integration purposes.
Full dataset for Los Angeles: /resources/data/los-angeles-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.