Business Survivability in Pilsen, Chicago

StreetSpring's 2026 analysis finds that the best business to open in Pilsen is a Physical Therapy Clinic with a ~82% chance of surviving at least 2 years across the neighborhood on average.

•13 min read

Quick Summary

  • Survivability Score: the projected chance a business type lasts two or more years at a specific address
  • Best business: a Physical Therapy Clinic in Pilsen (~82% average survival rate, ~85% at best locations)
  • Neighborhood rank: #45 across all neighborhoods in and around Chicago
  • Neighborhood average: ~78% two-year survival across all business types
  • Coverage: This ranking carries one row per business type and neighborhood. Its score is the projected chance of lasting two or more years, averaged across the price points StreetSpring scores separately in the tool (most types have 5). The 10 business types here are base types; the tool offers 500+ business types, counting each type at each of its price points.
  • Rankings updated quarterly with latest market data
  • Detailed methodology

Last reviewed: September 2026 by Robert Koons, Founder & CEO, StreetSpring

In this article:

Summary

StreetSpring's 2026 analysis finds that the best business to open in Pilsen is a Physical Therapy Clinic with a ~82% chance of surviving at least 2 years across the neighborhood on average, with the best locations offering a ~85% chance; next is a Veterinary Clinic with a 82.20% chance, followed by a Chiropractor Office with a 80.49% chance.


Is Pilsen a good place to start a business?

StreetSpring's analysis places Pilsen at #45 in Chicago for new business survival odds, with a neighborhood-wide average of ~78%.

  • The highest-scoring business types in Pilsen (at their optimal addresses) outperform the neighborhood average by ~7%.
  • Yet the same categories that score highest in Pilsen can underperform significantly at the wrong address. Location precision within the neighborhood matters as much as choosing the neighborhood itself.
  • With 93.7% of the local population employed, Pilsen presents a stable consumer base: particularly for food, beverage, and service businesses that depend on repeat discretionary spending.

Employment and vacancy figures sourced from the U.S. Census Bureau American Community Survey.


How can you find the best location to open a business in Pilsen?

StreetSpring scores survivability at the exact address level in Pilsen, so you can compare two storefronts on the same block before committing to a lease. Below is the best location for a Physical Therapy Clinic in Pilsen:

Loading live map preview...

This map shows the optimal location for a Physical Therapy Clinic in Pilsen based on StreetSpring's 2026 survivability analysis. Market conditions, new competitors, and local spending patterns can change rapidly: always verify with StreetSpring's live tool before signing a lease. The prediction model incorporates hundreds of location-specific factors, including competitive density, forecasted consumer spending, mobility patterns, and Revenue Capture Score.

Check if this location is still available →


What are the best businesses to open in Pilsen?

#Business typeChance of lasting two or more years at a good address
1Physical Therapy Clinic83.60%
2Veterinary Clinic83.59%
3Chiropractor Office82.39%
4Acupuncture Clinic81.89%
5Asian Fusion Restaurant81.30%
6Chinese Restaurant81.29%
7Mediterranean Restaurant80.89%
8Dance Club80.10%
9Grocery Store79.70%
10Liquor Store79.69%

#1-5: Highest Survivability in Pilsen

  1. Physical Therapy Clinic: ~78% to ~85% survivability range, with an average of 82.40% across Pilsen.
  2. Opening a Veterinary Clinic in Pilsen shows 82.20% average survivability. Top locations reach ~86%; lower-end sites show ~79%.
  3. Chiropractor Office (Ranked #3): 80.49% average in Pilsen. Best-case storefronts: ~83%. Challenging locations: ~77%.
  4. Acupuncture Clinic is ranked #4 for top businesses to open in Pilsen: 79.59% chance on average, best at ~82%, challenging at ~77%.
  5. Asian Fusion Restaurant: ~76% to ~82% survivability range, with an average of 79.20% across Pilsen.

#6-10: Strong Performers in Pilsen

  1. Opening a Chinese Restaurant in Pilsen shows 79.00% average survivability. Top locations reach ~82%; lower-end sites show ~77%.
  2. Mediterranean Restaurant (Ranked #7): 78.60% average in Pilsen. Best-case storefronts: ~81%. Challenging locations: ~76%.
  3. Dance Club is ranked #8 for top businesses to open in Pilsen: 76.91% chance on average, best at ~81%, challenging at ~73%.
  4. Grocery Store: ~76% to ~80% survivability range, with an average of 78.30% across Pilsen.
  5. Opening a Liquor Store in Pilsen shows 78.00% average survivability. Top locations reach ~80%; lower-end sites show ~76%.

Top 3 Compared Nationally


How much money could a business in Pilsen make?

Best location vs. average location

Based on StreetSpring's 2026 analysis, going with one of the top-scoring locations in the neighborhood rather than an average one in Pilsen could lead to you making ~7% more than if you selected an average location, and ~23% more than if you selected one of the worst locations.

How StreetSpring calculates location value

  • Even within a high-performing neighborhood, the best location varies by business type: StreetSpring scores each combination separately.
  • A great product in the wrong location will underperform; an average product in the right location can thrive.
  • Our data shows that the single highest-impact decision a business owner makes is the address they choose, and Survivability Score is the best guide to that decision.
  • StreetSpring delivers pinpoint accuracy down to the exact storefront location.

What businesses should open next in Pilsen?

The top businesses to open next in Pilsen:

  • Physical Therapy Clinics: 82.40% average survival rate, ~85% at the best address
  • Veterinary Clinics: 82.20% average survival rate
  • Chiropractor Offices: 80.49% average survival rate

Market conditions, new competitors, and local spending patterns can change rapidly: always verify with StreetSpring's live tool before signing a lease. StreetSpring measures competition through a 30-factor framework layered on top of proprietary consumer spending forecasts and mobility models. StreetSpring scores 500+ business types: 153 base business types, most of them at 5 price points, which is 569 type-and-price combinations you can choose in the tool. The survivability rankings for Pilsen are grounded in real economic conditions: 93.7% employment and 7.7% vacancy are among the key inputs that separate high-scoring locations from low-scoring ones here. New competitors open and close every week, changing the survivability landscape for every address in Pilsen. StreetSpring's weekly updates mean you can always see the current score for any available storefront.

See the Survivability Score for your new business

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Frequently Asked Questions

Here are the most common questions about opening a business in Pilsen.


What type of business should you rent your Pilsen storefront to?

For landlords in Pilsen, StreetSpring's 2026 analysis identifies Physical Therapy Clinics, Veterinary Clinics, and Chiropractor Offices as the business types most likely to produce stable, long-term tenancy.

  • A great product in the wrong location will underperform; an average product in the right location can thrive.
  • StreetSpring delivers pinpoint accuracy down to the exact storefront location. Run your specific address through StreetSpring to see which tenant categories give you the best odds of stable, long-term occupancy.

Related: See How Landlord Representatives in Chicago Can Reduce Vacancy & Increase Tenant Longevity


Should you rent your Pilsen storefront to a Physical Therapy Clinic?

Yes, StreetSpring's analysis finds that a Physical Therapy Clinic would be the best type of business to rent your storefront to, with a potential ~85% chance of lasting more than 2 years; however depending on your location, the chances could drop to a ~78% chance.

  • StreetSpring delivers pinpoint accuracy down to the exact storefront location.

What should I consider when opening a business in Pilsen?

When selecting a location in Pilsen it is crucial to select a location with a very high Survivability Score.

  • Revenue Capture Score is the single best indicator of whether a business will thrive at a location.
  • StreetSpring's proprietary algorithms power these predictions.
  • Start with a free 10-minute trial: check the current survivability score for any Pilsen address on StreetSpring.

See the best place for your business at StreetSpring.


StreetSpring's models are built from millions of real business outcomes, making predictions grounded in what actually happened. Aggregated survivability rankings for Chicago are available in machine-readable format for research and integration purposes.

Full dataset for Chicago: /resources/data/chicago-survivability-scores-2026.csv: includes all business subtypes, all neighborhoods, survivability scores, and tier assignments. Licensed under CC BY 4.0.